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Perspectives in Diabetes

+ Author Affiliations

Diabetes 2010 Nov; 59 (11): 2717 - 2725. https://doi.org/10.2337/db10-0822
Previous

Perhaps the greatest barriers to achieving major public health advances in the 21st century will result from pandemic paradigm paralysis or the widespread inability to envision alternative or new models of thinking. One potential example of this phenomenon could turn out to be the continued focus on moderate and vigorous physical activity as the dominant health-related aspect of human movement. The current model of physical activity and health is well supported by over 60 years of scientific inquiry, and the beneficial effects of moderate-to-vigorous physical activity have been more clearly defined in recent years ( 1 4 ). However, if we are complacent with the existing paradigm—that increasing levels of moderate and vigorous levels of physical activity will result in the greatest improvements in public health—then we may not obtain the full return on investment with respect to improving quality of life and life expectancy through patterns of human movement. Emerging evidence for the role of sedentary behavior on health, which may be independent of physical activity per se, finds us at a crossroad with respect to prescribing optimal daily human movement patterns for health.

Human movement represents a complex behavior that is influenced by personal motivation, health and mobility issues, genetic factors, and the social and physical environments in which people live. These factors undoubtedly exert an influence on the propensity to engage in sedentary behaviors as well as in physical activity. However, the biological, social, and environmental pathways leading to sedentary behavior versus physical activity may be different. Further, the health effects associated with sedentary behavior and physical activity may be the result of different biological mechanisms ( Hermes T 46 Coat In Taupe Reindeer Hermès Deals Sale Online Cheap Sale Shopping Online Lzsohuo
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Energy balance has been a central selective force throughout human evolutionary history, and humans have evolved to have high levels of energy expenditure, even more so than modern nonhuman primates ( Balenciaga Bouclé MohairBlend Jacket Discount Classic Cheap Wholesale Clearance Cheap Price Cheap Authentic Outlet Buy Cheap Professional IMJpJ8
). Obtaining dietary energy and nutrients from the environment traditionally required an expenditure of energy through human movement. Factors related to the expansion of the African grasslands between 2.5 and 1.5 million years ago and the emergence of Homo were major contributors to changes in both brain size and foraging behaviors ( 6 , shortsleeved ribbed jumper Grey Chloé High-Quality Cheap WKunjuEEU
). Early Homo ( H. habilis and H. erectus ) appeared at a time of rapid brain evolution with early Homo having an average brain size of 600–900 cc compared with earlier australopithecines with an average brain size of 400–500 cc ( Sheer amp; Solid Silk Blazer Karl Lagerfeld Shop For Cheap Online Footaction Sale Online Cheap Buy Authentic vQaxuIAK
). The larger brain size of Homo required higher quality diets, which necessitated larger foraging ranges, resulting in greater total energy expenditure. At the same time, the transition from a forest to savanna environment caused changes in resource distribution that would have also resulted in increases in foraging ranges and total energy expenditure ( 6 ). Much of human evolution has occurred as hunter-gatherers (3–4 million years), while recent advances in agriculture and technology have occurred over a short time frame (∼10,000 years). Eaton and Eaton ( 8 ) have estimated that Stone Age humans had an energy efficiency ratio of 2.25 (i.e., expending 1 kJ of energy to acquire 2.25 kJ of dietary energy) compared with an efficiency ratio of 3.66 for modern humans, which represents more than a 50% increase in efficiency.

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Video: a look at conduct

Pronunciation /ˈkɒndʌkt/

1 The manner in which a person behaves, especially in a particular place or situation.

behaviour , way of behaving, performance, comportment, demeanour, bearing, deportment

2 The manner in which an organization or activity is managed or directed.

management , managing, running, direction, control, controlling, overseeing, supervision, regulation, leadership, masterminding, administration, organization, coordination, orchestration, handling, guidance, carrying out, carrying on
Pronunciation /kənˈdʌkt/

1 Organize and carry out.

manage , direct, run, be in control of, control, oversee, supervise, be in charge of, preside over, regulate, mastermind, administer, organize, coordinate, orchestrate, handle, guide, govern, lead, carry out, carry on

2 Lead or guide (someone) to or around a particular place.

escort , guide, lead, usher, pilot, accompany, show, show someone the way

3 Physics Transmit (a form of energy such as heat or electricity) by conduction.

transmit , convey, carry, transfer, pass on, hand on, communicate, impart, channel, bear, relay, dispatch, mediate

4 Direct the performance of (a piece of music or an orchestra, choir, etc.)

5 conduct oneself Behave in a specified way.

conduct oneself
behave , perform, act, acquit oneself, bear oneself, carry oneself

Origin

Middle English: from Old French, from Latin conduct- ‘brought together’, from the verb conducere. The term originally denoted a provision for safe passage, surviving in safe conduct; later the verb sense ‘lead, guide’ arose, hence ‘manage’ and ‘management’ ( late Middle English), later ‘management of oneself, behaviour’ (mid 16th century). The original form of the word was conduit, which was preserved only in the sense ‘channel’ (see conduit); in other uses the spelling was influenced by Latin.

Pronunciation

28. Farnsworth, A. Interpretation of the Contract , [Bianca-Bonell Commentary, Milan: Giuffré (1987)], no. 5 at p. 99.

29. Paragraph 3 of art. 8 of the UN Sales Convention was inspired by art. 9 (para. 3 of ULIS which laid down the instruction of interpretation of the "expressions, provisions or forms of contract commonly used in commercial practice". Their interpretation, according the ULIS, shall be "according to the meaning usually given to them in the trade concerned".

Citing the numerous references to reasonableness in the CISG ["arts. 46(3) sentences 1 and 2, 49(2), 63(1), 65(2), 72(1), 73(2), 75, 77, 79(1), 85 sentence 1, 87, 88(1), 88(2) and 88(3)"] Schlechtriem states that "the rule that the parties must conduct themselves according to the standard of the 'reasonable person' . . . must be regarded as a general principle of the Convention". [1]

References to reasonableness may also be found in arts. 8(2) and (3), 16(2)(b), 18(2), 25, 33(c), 34, 35(1)(b), 37, 38(3), 39(1), 43(1), 44, 47(1), 48(1) and (2), 60(a), 64(2)(b), 72(2), 76(2), 79(4) and 86(1). For extrapolations of the concept of the "reasonable person" to still other parts of the CISG -- arts. 9 and 74, for example -- see van der Velden [2] who also cites Tesa v. Amram [3] as an illustrative judicial precedent for reasonableness as a general principle of the Convention. The issue before the court was the reasonableness of the length of the period of time set for payment according to article 62, section 2, ULIS. The court stated: "The Uniform Law on International Sale . . . uses in its articles 10, 11, 13, 22, 26(1), 26(4), 37, 42(2), 61(2), 66(2), 74, 88 and 91 the words 'reasonable', 'unreasonable' and 'reasonably'; 'reasonableness' is therefore one of the general principles by which, in accordance with Article 17 ULIS, the questions not expressly settled in the uniform sales law shall be answered. . . ." Very Cheap Cushnie et Ochs Silk Midi Dress Best Wholesale Sale Online Discount Latest 3bAIx9y3s

Van der Velden interprets the concept of reasonableness as connoting, among other things, "an ethical standard of behavior so that [one] must . . . be judicious and fair". T by Alexander Wang Short Sleeve KneeLength Dress Online Cheap Online tUnQ1
Maskow calls attention to the fact that reasonableness is to be defined according to its meaning in socialist, developing and developed market economy countries, not simply in developed market-economy countries. [6] Bonell also states that "in applying . . . the 'reasonableness' test in order to determine whether a party in a particular circumstance has been (re-)acting with due diligence, a judge of a highly industrialized country may not automatically refer to the standards of care and professional skill normally required from national business people in domestic affairs. The answer should be found either in the Convention itself or at least on the basis of standards which are currently adopted also in other legal systems." [7]

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British World English communication

1 mass noun The imparting or exchanging of information by speaking, writing, or using some other medium.

transmission , imparting, conveying, reporting, presenting, passing on, handing on, relay, conveyance, divulgence, divulgation, disclosure
message , statement, announcement, report, dispatch, communiqué, letter, bulletin, correspondence, news, word, information, intelligence, instruction
contact , dealings, relations, connection, association, communion, socializing, intercourse, social intercourse, social relations, interface, interchange, correspondence, dialogue, talk, conversation, discussion, speaking, talking, chatting, meeting, getting in touch

2 communications Means of sending or receiving information, such as telephone lines or computers.

communications
as modifier

3 communications Means of travelling or of transporting goods, such as roads or railways.

links , connections, services, routes

Origin

Late Middle English: from Old French comunicacion, from Latin communicatio(n-), from the verb communicare ‘to share’ (see communicate).

Pronunciation

communication

/kəmjuːnɪˈkeɪʃ(ə)n/
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'-ch' or '-tch'?
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